Lactate dehydrogenase (LDH) is an enzyme with wide tissue distribution in the body.  The higher concentrations of LDH are found in liver, heart, kidney, skeletal muscle and erythrocytes. Increased levels of the enzyme are found in serum in liver disease, myocardial infarction, renal disease, muscular dystrophy and anemia. Clinical diagnosis should not be made on a single test result; it should integrate clinical and other laboratory data.