α-Amylase (AMS) is an enzyme that helps to digest the glycogen and the starch. It is produced mainly by exocrine pancreas and salivary glands. This determination is made mainly in diagnosis or to control diseases of the pancreas as acute or chronic pancreatitis. It can also reflect biliary or gastrointestinal disease and other upheavals Clinical diagnosis should not be made on a single test result; it should integrate clinical and other laboratory data.