HDL particles are high-density lipoproteins that transport cholesterol from the body tissues to the liver. Since HDL can remove cholesterol from the arteries and carry it back to the liver for their excretion, HDL is known as “good cholesterol” because high levels are thought to lower the risk of heart disease and coronary artery disease. A low HDL cholesterol levels, is considered a greater heart disease risk. Clinical diagnosis should not be made on a single test result; it should integrate clinical and other laboratory data.